The RAC1 activator Tiam1 regulates centriole duplication through controlling PLK4 levels
The RAC1 activator Tiam1 regulates centriole duplication through controlling PLK4 levels
About this item
Full title
Author / Creator
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
Formats
Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Subjects
More information
Scope and Contents
Contents
Centriole duplication is tightly controlled to maintain correct centriole number through the cell cycle. A key component of this control is the regulated degradation of PLK4, the master regulator of centriole duplication. Here we show that the Rac1 guanine nucleotide exchange factor (GEF) Tiam1 localises to centrosomes during S-phase, where it is r...
Alternative Titles
Full title
The RAC1 activator Tiam1 regulates centriole duplication through controlling PLK4 levels
Authors, Artists and Contributors
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2405102719
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2405102719
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2020.05.20.106120
How to access this item
https://www.proquest.com/docview/2405102719?pq-origsite=primo&accountid=13902
