N-acetylaspartate improves cell survival when glucose is limiting
N-acetylaspartate improves cell survival when glucose is limiting
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
N-acetylasparate (NAA), previously considered a brain-specific metabolite, is found in several cancers. However, whether it plays a role in tumor growth or survival is not fully understood. We provide evidence that NAA prevents cell death in low-glucose conditions via sustaining intracellular UDP-N-acetylglucosamine (UDP-GlcNac) levels, suppressing...
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Full title
N-acetylaspartate improves cell survival when glucose is limiting
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TN_cdi_proquest_journals_2407796314
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2407796314
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E-ISSN
2692-8205
DOI
10.1101/2020.05.28.114629
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https://www.proquest.com/docview/2407796314?pq-origsite=primo&accountid=13902
