Single-cell Transcriptomics Identifies Gene Expression Networks Driving Differentiation and Tumorige...
Single-cell Transcriptomics Identifies Gene Expression Networks Driving Differentiation and Tumorigenesis in the Human Fallopian Tube
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Author / Creator
Dinh, Huy Q , Lin, Xianzhi , Abbasi, ough , Nameki, Robbin , Haro, Marcela , Olingy, Claire , Chang, Heidi , Hernandez, Lourdes , Gayther, Simon , Wright, Kelly N , Paul-Joseph Aspuria , Karlan, Beth , Corona, Rosario I , Li, Andrew , Rimel, Bj , Siedhoff, Matthew , Medeiros, Fabiola and Lawrenson, Kate
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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The human fallopian tube harbors the cell-of-origin for the majority of high-grade serous ovarian cancers (HGSCs), but its cellular composition, particularly the epithelial component, is poorly characterized. We performed single-cell transcriptomic profiling in 12 primary fallopian specimens from 8 patients, analyzing around 53,000 individual cells...
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Single-cell Transcriptomics Identifies Gene Expression Networks Driving Differentiation and Tumorigenesis in the Human Fallopian Tube
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TN_cdi_proquest_journals_2407796402
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2407796402
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E-ISSN
2692-8205
DOI
10.1101/2020.05.28.119933
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https://www.proquest.com/docview/2407796402?pq-origsite=primo&accountid=13902
