Use of signals of positive and negative selection to distinguish cancer genes and passenger genes
Use of signals of positive and negative selection to distinguish cancer genes and passenger genes
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Abstract Background A major goal of cancer genomics is to identify all genes that play critical roles in carcinogenesis. Most of the approaches aimed to achieve this goal focused on genes that are positively selected for mutations that drive carcinogenesis and neglected the role of negative selection. Some studies have actually concluded that negat...
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Full title
Use of signals of positive and negative selection to distinguish cancer genes and passenger genes
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TN_cdi_proquest_journals_2409778347
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2409778347
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E-ISSN
2692-8205
DOI
10.1101/2020.06.04.133199
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https://www.proquest.com/docview/2409778347?pq-origsite=primo&accountid=13902
