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Combining genome-wide studies of breast, prostate, ovarian and endometrial cancers maps cross-cancer...

Combining genome-wide studies of breast, prostate, ovarian and endometrial cancers maps cross-cancer...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2414912759

Combining genome-wide studies of breast, prostate, ovarian and endometrial cancers maps cross-cancer susceptibility loci and identifies new genetic associations

About this item

Full title

Combining genome-wide studies of breast, prostate, ovarian and endometrial cancers maps cross-cancer susceptibility loci and identifies new genetic associations

Author / Creator

Kar, Siddhartha P , Lindstroem, Sara , Hung, Rayjean , Lawrenson, Kate , Schmidt, Marjanka , O'mara, Tracy , Glubb, Dylan , Tyrer, Jonathan , Schildkraut, Joellen , Chang-Claude, Jenny , Alsulimani, Ahmad , Anton, Fernando , Beeghly-Fadiel, Alicia , Bjorge, Line , Bodelon, Clara , Brauch, Hiltrud , Burghaus, Stefanie , Campa, Daniele , Carney, Michael , Chen, Zhihua , Daly, Mary , Andreas Du Bois , Ekici, Arif , Ewing, Ailith , Fasching, Peter , Flanagan, James M , Gawelko, Jan , Giles, Graham , Hamilton, Robert , Harris, Holly , Heitz, Florian , Hildebrandt, Michelle , Hillemanns, Peter , Huang, Ruea-Yea , Imaz, Liher , Irmejs, Arvids , Jakubowska, Anna , Jensen, Allan , Esther, John , Kannisto, Paivi , Karlan, Beth , Khusnutdinova, Elza , Kiemeney, Lambertus , Kjaer, Susanne , Klapdor, Rudiger , Kleiblova, Petra , Koebel, Martin , Konopka, Bozena , Krakstad, Camilla , Lessel, Davor , Lophatananon, Artitaya , May, Taymaa , Mieszkowska, Agnieszka , Monteiro, Alvaro , Moysich, Kirsten , Muir, Kenneth , Nielsen, Sune , Odunsi, Kunle , Olsson, Hakan , Park-Simon, Tjoung-Won , Permuth, Jennifer , Peterlongo, Paolo , Podgorski, Agnieszka , Radice, Paolo , Risch, Harvey , Runnebaum, Ingo , Rzepecka, Iwona , Setiawan, Veronica , Siddiqui, Nadeem , Sieh, Weiva , Spiewankiewicz, Beata , Szafron, Lukasz , Thompson, Cheryl , Titus, Linda , Turnbull, Clare , Usmani, Nawaid , Anne Van Altena , Vega-Gliemmo, Ana , Vergote, Ignace , Vierkant, Robert , Vijai, Joseph , Winham, Stacey , Winqvist, Robert , Yu, Herbert , Thompson, Deborah , Zheng, Wei , Tomlinson, Ian , Berchuck, Andrew , Ramus, Susan , Chanock, Stephen , Easton, Douglas , Chenevix-Trench, Georgia , Gayther, Simon , Spurdle, Amanda , Eeles, Rosalind , Kraft, Peter and Pharoah, Paul

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2020-06

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

We report a meta-analysis of breast, prostate, ovarian, and endometrial cancer genome-wide association data (effective sample size: 237,483 cases/317,006 controls). This identified 465 independent lead variants (P<5x10-8) across 192 genomic regions. Four lead variants were >1Mb from previously identified risk loci for the four cancers and an additi...

Alternative Titles

Full title

Combining genome-wide studies of breast, prostate, ovarian and endometrial cancers maps cross-cancer susceptibility loci and identifies new genetic associations

Authors, Artists and Contributors

Author / Creator

Kar, Siddhartha P
Lindstroem, Sara
Hung, Rayjean
Lawrenson, Kate
Schmidt, Marjanka
O'mara, Tracy
Glubb, Dylan
Tyrer, Jonathan
Schildkraut, Joellen
Chang-Claude, Jenny
Alsulimani, Ahmad
Anton, Fernando
Beeghly-Fadiel, Alicia
Bjorge, Line
Bodelon, Clara
Brauch, Hiltrud
Burghaus, Stefanie
Campa, Daniele
Carney, Michael
Chen, Zhihua
Daly, Mary
Andreas Du Bois
Ekici, Arif
Ewing, Ailith
Fasching, Peter
Flanagan, James M
Gawelko, Jan
Giles, Graham
Hamilton, Robert
Harris, Holly
Heitz, Florian
Hildebrandt, Michelle
Hillemanns, Peter
Huang, Ruea-Yea
Imaz, Liher
Irmejs, Arvids
Jakubowska, Anna
Jensen, Allan
Esther, John
Kannisto, Paivi
Karlan, Beth
Khusnutdinova, Elza
Kiemeney, Lambertus
Kjaer, Susanne
Klapdor, Rudiger
Kleiblova, Petra
Koebel, Martin
Konopka, Bozena
Krakstad, Camilla
Lessel, Davor
Lophatananon, Artitaya
May, Taymaa
Mieszkowska, Agnieszka
Monteiro, Alvaro
Moysich, Kirsten
Muir, Kenneth
Nielsen, Sune
Odunsi, Kunle
Olsson, Hakan
Park-Simon, Tjoung-Won
Permuth, Jennifer
Peterlongo, Paolo
Podgorski, Agnieszka
Radice, Paolo
Risch, Harvey
Runnebaum, Ingo
Rzepecka, Iwona
Setiawan, Veronica
Siddiqui, Nadeem
Sieh, Weiva
Spiewankiewicz, Beata
Szafron, Lukasz
Thompson, Cheryl
Titus, Linda
Turnbull, Clare
Usmani, Nawaid
Anne Van Altena
Vega-Gliemmo, Ana
Vergote, Ignace
Vierkant, Robert
Vijai, Joseph
Winham, Stacey
Winqvist, Robert
Yu, Herbert
Thompson, Deborah
Zheng, Wei
Tomlinson, Ian
Berchuck, Andrew
Ramus, Susan
Chanock, Stephen
Easton, Douglas
Chenevix-Trench, Georgia
Gayther, Simon
Spurdle, Amanda
Eeles, Rosalind
Kraft, Peter
Pharoah, Paul

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2414912759

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2414912759

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2020.06.16.146803