Dimeric prion protein ligand activates Adgrg6 but does not rescue myelinopathy of PrP-deficient mice
Dimeric prion protein ligand activates Adgrg6 but does not rescue myelinopathy of PrP-deficient mice
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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The adhesion G-protein coupled receptor Adgrg6 (formerly Gpr126) is instrumental in the development, maintenance and repair of peripheral nervous system myelin. The prion protein (PrP) is a potent activator of Adgrg6 and could be used as a potential therapeutic agent in treating peripheral demyelinating and dysmyelinating diseases. We designed a di...
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Dimeric prion protein ligand activates Adgrg6 but does not rescue myelinopathy of PrP-deficient mice
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TN_cdi_proquest_journals_2420905356
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2420905356
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E-ISSN
2692-8205
DOI
10.1101/2020.07.07.191452
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https://www.proquest.com/docview/2420905356?pq-origsite=primo&accountid=13902
