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Pharmacokinetic profile of the selective 5-HT3 receptor antagonist ondansetron in the rat: an origin...

Pharmacokinetic profile of the selective 5-HT3 receptor antagonist ondansetron in the rat: an origin...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2421163023

Pharmacokinetic profile of the selective 5-HT3 receptor antagonist ondansetron in the rat: an original study and a minireview of the behavioural pharmacological literature in the rat

About this item

Full title

Pharmacokinetic profile of the selective 5-HT3 receptor antagonist ondansetron in the rat: an original study and a minireview of the behavioural pharmacological literature in the rat

Publisher

1840 Woodward Drive, Suite 1, Ottawa, ON K2C 0P7: NRC Research Press

Journal title

Canadian journal of physiology and pharmacology, 2020, Vol.98 (7), p.431-440

Language

English

Formats

Publication information

Publisher

1840 Woodward Drive, Suite 1, Ottawa, ON K2C 0P7: NRC Research Press

More information

Scope and Contents

Contents

The availability of agonists and antagonists to modulate the activity of the 5-hydroxytryptamine (5-HT) type 3 (5-HT
3
) receptor has renewed interest in its role as a therapeutic target. Ondansetron is a highly selective 5-HT
3
receptor antagonist that is well tolerated as an anti-emetic for patients undergoing chemotherapy. Preclinica...

Alternative Titles

Full title

Pharmacokinetic profile of the selective 5-HT3 receptor antagonist ondansetron in the rat: an original study and a minireview of the behavioural pharmacological literature in the rat

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2421163023

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2421163023

Other Identifiers

ISSN

0008-4212

E-ISSN

1205-7541

DOI

10.1139/cjpp-2019-0551

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