Genetic variations and haplotype structures of the DPYD gene encoding dihydropyrimidine dehydrogenas...
Genetic variations and haplotype structures of the DPYD gene encoding dihydropyrimidine dehydrogenase in Japanese and their ethnic differences
About this item
Full title
Author / Creator
Maekawa, Keiko , Saeki, Mayumi , Saito, Yoshiro , Ozawa, Shogo , Kurose, Kouichi , Kaniwa, Nahoko , Kawamoto, Manabu , Kamatani, Naoyuki , Kato, Ken , Hamaguchi, Tetsuya , Yamada, Yasuhide , Shirao, Kuniaki , Shimada, Yasuhiro , Muto, Manabu , Doi, Toshihiko , Ohtsu, Atsushi , Yoshida, Teruhiko , Matsumura, Yasuhiro , Saijo, Nagahiro and Sawada, Jun-ichi
Publisher
Tokyo: Springer Japan
Journal title
Language
English
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Publication information
Publisher
Tokyo: Springer Japan
Subjects
More information
Scope and Contents
Contents
Dihydropyrimidine dehydrogenase (DPD) is an inactivating and rate-limiting enzyme for 5-fluorouracil (5-FU), and its deficiency is associated with a risk for developing a severe or fatal toxicity to 5-FU. In this study, to search for genetic variations of
DPYD
encoding DPD in Japanese, the putative promoter region, all exons, and flanking int...
Alternative Titles
Full title
Genetic variations and haplotype structures of the DPYD gene encoding dihydropyrimidine dehydrogenase in Japanese and their ethnic differences
Authors, Artists and Contributors
Author / Creator
Saeki, Mayumi
Saito, Yoshiro
Ozawa, Shogo
Kurose, Kouichi
Kaniwa, Nahoko
Kawamoto, Manabu
Kamatani, Naoyuki
Kato, Ken
Hamaguchi, Tetsuya
Yamada, Yasuhide
Shirao, Kuniaki
Shimada, Yasuhiro
Muto, Manabu
Doi, Toshihiko
Ohtsu, Atsushi
Yoshida, Teruhiko
Matsumura, Yasuhiro
Saijo, Nagahiro
Sawada, Jun-ichi
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2425618238
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2425618238
Other Identifiers
ISSN
1434-5161
E-ISSN
1435-232X
DOI
10.1007/s10038-007-0186-6
