Hepatocytic transcriptional signatures predict comparative drug interaction potential of rifamycin a...
Hepatocytic transcriptional signatures predict comparative drug interaction potential of rifamycin antibiotics
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
Current strategies to treat tuberculosis (TB) and co-morbidities involve multidrug combination therapies. Rifamycin antibiotics are a key component of TB therapy and a common source of drug–drug interactions (DDIs) due to induction of drug metabolizing enzymes (DMEs). Management of rifamycin DDIs are complex, particularly in patients with co-morbid...
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Full title
Hepatocytic transcriptional signatures predict comparative drug interaction potential of rifamycin antibiotics
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TN_cdi_proquest_journals_2427535022
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2427535022
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ISSN
2045-2322
E-ISSN
2045-2322
DOI
10.1038/s41598-020-69228-z
