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Endothelin receptor heteromerization inhibits β-arrestin function in HEK293 cells

Endothelin receptor heteromerization inhibits β-arrestin function in HEK293 cells

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2432566768

Endothelin receptor heteromerization inhibits β-arrestin function in HEK293 cells

About this item

Full title

Endothelin receptor heteromerization inhibits β-arrestin function in HEK293 cells

Publisher

1840 Woodward Drive, Suite 1, Ottawa, ON K2C 0P7: NRC Research Press

Journal title

Canadian journal of physiology and pharmacology, 2020-08, Vol.98 (8), p.531-540

Language

English

Formats

Publication information

Publisher

1840 Woodward Drive, Suite 1, Ottawa, ON K2C 0P7: NRC Research Press

More information

Scope and Contents

Contents

The endothelin receptor A (ETA) and endothelin receptor B (ETB) are G protein-coupled receptors that are co-expressed in vascular smooth muscle cells. Endothelin-1 (ET-1) activates endothelin receptors to cause microvascular vasoconstriction. Previous studies have shown that heteromerization between ETA and ETB prolongs Ca
2+
transients, lead...

Alternative Titles

Full title

Endothelin receptor heteromerization inhibits β-arrestin function in HEK293 cells

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2432566768

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2432566768

Other Identifiers

ISSN

0008-4212

E-ISSN

1205-7541

DOI

10.1139/cjpp-2019-0620

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