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Chondroitinase and antidepressants promote plasticity by releasing TRKB from dephosphorylating contr...

Chondroitinase and antidepressants promote plasticity by releasing TRKB from dephosphorylating contr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2433627186

Chondroitinase and antidepressants promote plasticity by releasing TRKB from dephosphorylating control of PTPσ in parvalbumin neurons

About this item

Full title

Chondroitinase and antidepressants promote plasticity by releasing TRKB from dephosphorylating control of PTPσ in parvalbumin neurons

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2020-11

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Abstract Perineuronal nets (PNNs) are an extracellular matrix structure rich in chondroitin sulphate proteoglycans (CSPGs) which preferentially encase parvalbumin-containing (PV+) interneurons. PNNs restrict cortical network plasticity but the molecular mechanisms involved are unclear. We found that reactivation of ocular dominance plasticity in th...

Alternative Titles

Full title

Chondroitinase and antidepressants promote plasticity by releasing TRKB from dephosphorylating control of PTPσ in parvalbumin neurons

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2433627186

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2433627186

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2020.08.13.249615