Suppression of p16 alleviates the senescence-associated secretory phenotype
Suppression of p16 alleviates the senescence-associated secretory phenotype
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
Oncogene induced senescence (OIS) is characterized by increased expression of the cell cycle inhibitor p16, leading to a hallmark cell cycle arrest. Suppression of p16 in this context drives proliferation, senescence bypass, and contributes to tumorigenesis. OIS cells are also characterized by the expression and secretion of a widely variable group...
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Full title
Suppression of p16 alleviates the senescence-associated secretory phenotype
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TN_cdi_proquest_journals_2435337002
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2435337002
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E-ISSN
2692-8205
DOI
10.1101/2020.08.19.257717
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https://www.proquest.com/docview/2435337002?pq-origsite=primo&accountid=13902
