Preexisting memory CD4 T cells in naïve individuals confer robust immunity upon hepatitis B vaccinat...
Preexisting memory CD4 T cells in naïve individuals confer robust immunity upon hepatitis B vaccination
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Author / Creator
Elias, George , Meysman, Pieter , Bartholomeus, Esther , De Neuter, Nicolas , Keersmaekers, Nina , Suls, Arvid , Jansens, Hilde , Souquette, Aisha , De Reu, Hans , Smits, Evelien , Lion, Eva , Thomas, Paul G , Mortier, Geert , Pierre Van Damme , Beutels, Philippe , Laukens, Kris , Viggo Van Tendeloo and Benson Ogunjimi
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Summary Antigen recognition through the T cell receptor (TCR) αβ heterodimer is one of the primary determinants of the adaptive immune response. Vaccines activate naïve T cells with high specificity to expand and differentiate into memory T cells. However, antigen-specific memory CD4 T cells exist in unexposed antigen-naïve hosts. In this study, we...
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Full title
Preexisting memory CD4 T cells in naïve individuals confer robust immunity upon hepatitis B vaccination
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TN_cdi_proquest_journals_2436982139
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2436982139
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E-ISSN
2692-8205
DOI
10.1101/2020.08.22.262568
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https://www.proquest.com/docview/2436982139?pq-origsite=primo&accountid=13902
