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DNA methylation landscapes of matched primary and recurrent high grade serous ovarian cancers are pr...

DNA methylation landscapes of matched primary and recurrent high grade serous ovarian cancers are pr...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2437277038

DNA methylation landscapes of matched primary and recurrent high grade serous ovarian cancers are preserved throughout disease progression and chemoresistance

About this item

Full title

DNA methylation landscapes of matched primary and recurrent high grade serous ovarian cancers are preserved throughout disease progression and chemoresistance

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2020-08

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Little is known about the role of global DNA methylation in recurrence and chemoresistance of high grade serous ovarian cancer (HGSOC). We performed whole genome bisulfite sequencing (WGBS) and whole transcriptome sequencing (RNA-seq) to establish methylation and gene expression signatures in 62 primary and recurrent tumors from 28 patients diagnos...

Alternative Titles

Full title

DNA methylation landscapes of matched primary and recurrent high grade serous ovarian cancers are preserved throughout disease progression and chemoresistance

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2437277038

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2437277038

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2020.08.25.267161