Highly potent anti-SARS-CoV-2 multivalent DARPin therapeutic candidates
Highly potent anti-SARS-CoV-2 multivalent DARPin therapeutic candidates
About this item
Full title
Author / Creator
Walser, Marcel , Rothenberger, Sylvia , Hurdiss, Daniel L , Schlegel, Anja , Calabro, Valerie , Fontaine, Simon , Villemagne, Denis , Paladino, Maria , Hospodarsch, Tanja , Neculcea, Alexandra , Cornelius, Andreas , Schildknecht, Patricia , Matzner, Mirela , Haenggi, Martin , Franchini, Marco , Kaufmann, Yvonne , Schaible, Doris , Schlegel, Iris , Iss, Chloe , Looser, Thamar , Mangold, Susanne , Herzog, Christel , Schiegg, Dieter , Reichen, Christian , Radom, Filip , Bosshart, Andreas , Lehmann, Andreas , Haeuptle, Micha A , Zuercher, Alexander , Vagt, Toni , Sigrist, Gabriel , Straumann, Marcel , Proba, Karl , Veitonmaki, Niina , Dawson, Keith M , Zitt, Christof , Mayor, Jennifer , Ryter, Sarah , Lyoo, Heyrhyoung , Wang, Chunyan , Li, Wentao , Drulyte, Ieva , Du, Wenjuan , H Kaspar Binz , Leon De Waal , Stittelaar, Koert J , Taplin, Sarah , Lewis, Seth , Steiner, Daniel , Van Kuppeveld, Frank Jm , Engler, Olivier , Bosch, Berend-Jan , Stumpp, Michael T and Amstutz, Patrick
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
Formats
Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Subjects
More information
Scope and Contents
Contents
Globally accessible therapeutics against SARS-CoV-2 are urgently needed. Here, we report the generation of the first anti-SARS-CoV-2 DARPin molecules with therapeutic potential as well as rapid large-scale production capabilities. Highly potent multivalent DARPin molecules with low picomolar virus neutralization efficacies were generated by molecul...
Alternative Titles
Full title
Highly potent anti-SARS-CoV-2 multivalent DARPin therapeutic candidates
Authors, Artists and Contributors
Author / Creator
Rothenberger, Sylvia
Hurdiss, Daniel L
Schlegel, Anja
Calabro, Valerie
Fontaine, Simon
Villemagne, Denis
Paladino, Maria
Hospodarsch, Tanja
Neculcea, Alexandra
Cornelius, Andreas
Schildknecht, Patricia
Matzner, Mirela
Haenggi, Martin
Franchini, Marco
Kaufmann, Yvonne
Schaible, Doris
Schlegel, Iris
Iss, Chloe
Looser, Thamar
Mangold, Susanne
Herzog, Christel
Schiegg, Dieter
Reichen, Christian
Radom, Filip
Bosshart, Andreas
Lehmann, Andreas
Haeuptle, Micha A
Zuercher, Alexander
Vagt, Toni
Sigrist, Gabriel
Straumann, Marcel
Proba, Karl
Veitonmaki, Niina
Dawson, Keith M
Zitt, Christof
Mayor, Jennifer
Ryter, Sarah
Lyoo, Heyrhyoung
Wang, Chunyan
Li, Wentao
Drulyte, Ieva
Du, Wenjuan
H Kaspar Binz
Leon De Waal
Stittelaar, Koert J
Taplin, Sarah
Lewis, Seth
Steiner, Daniel
Van Kuppeveld, Frank Jm
Engler, Olivier
Bosch, Berend-Jan
Stumpp, Michael T
Amstutz, Patrick
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2437277102
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2437277102
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2020.08.25.256339
How to access this item
https://www.proquest.com/docview/2437277102?pq-origsite=primo&accountid=13902
