Capmatinib in MET Exon 14–Mutated or MET-Amplified Non–Small-Cell Lung Cancer
Capmatinib in MET Exon 14–Mutated or MET-Amplified Non–Small-Cell Lung Cancer
About this item
Full title
Author / Creator
Wolf, Jürgen , Seto, Takashi , Han, Ji-Youn , Reguart, Noemi , Garon, Edward B , Groen, Harry J.M , Tan, Daniel S.W , Hida, Toyoaki , de Jonge, Maja , Orlov, Sergey V , Smit, Egbert F , Souquet, Pierre-Jean , Vansteenkiste, Johan , Hochmair, Maximilian , Felip, Enriqueta , Nishio, Makoto , Thomas, Michael , Ohashi, Kadoaki , Toyozawa, Ryo , Overbeck, Tobias R , de Marinis, Filippo , Kim, Tae-Min , Laack, Eckart , Robeva, Anna , Le Mouhaer, Sylvie , Waldron-Lynch, Maeve , Sankaran, Banu , Balbin, O. Alejandro , Cui, Xiaoming , Giovannini, Monica , Akimov, Mikhail and Heist, Rebecca S
Publisher
Boston: Massachusetts Medical Society
Journal title
Language
English
Formats
Publication information
Publisher
Boston: Massachusetts Medical Society
Subjects
More information
Scope and Contents
Contents
MET
is altered by skipping exon 14 or gene amplification in 1 to 2% of patients with non–small-cell lung cancer. Capmatinib, a
MET
-specific tyrosine kinase inhibitor, led to a response in 40% of previously treated patients and in 67% of previously untreated patients whose tumors had
MET
alterations, with a median response duration o...
Alternative Titles
Full title
Capmatinib in MET Exon 14–Mutated or MET-Amplified Non–Small-Cell Lung Cancer
Authors, Artists and Contributors
Author / Creator
Seto, Takashi
Han, Ji-Youn
Reguart, Noemi
Garon, Edward B
Groen, Harry J.M
Tan, Daniel S.W
Hida, Toyoaki
de Jonge, Maja
Orlov, Sergey V
Smit, Egbert F
Souquet, Pierre-Jean
Vansteenkiste, Johan
Hochmair, Maximilian
Felip, Enriqueta
Nishio, Makoto
Thomas, Michael
Ohashi, Kadoaki
Toyozawa, Ryo
Overbeck, Tobias R
de Marinis, Filippo
Kim, Tae-Min
Laack, Eckart
Robeva, Anna
Le Mouhaer, Sylvie
Waldron-Lynch, Maeve
Sankaran, Banu
Balbin, O. Alejandro
Cui, Xiaoming
Giovannini, Monica
Akimov, Mikhail
Heist, Rebecca S
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2439673508
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2439673508
Other Identifiers
ISSN
0028-4793
E-ISSN
1533-4406
DOI
10.1056/NEJMoa2002787
