Phenylalkylamines in calcium channels: computational analysis of experimental structures
Phenylalkylamines in calcium channels: computational analysis of experimental structures
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Cham: Springer International Publishing
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Language
English
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Cham: Springer International Publishing
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Contents
Experimental 3D structures of calcium channels with phenylalkylamines (PAAs) provide basis for further analysis of atomic mechanisms of these important cardiovascular drugs. In the crystal structure of the engineered calcium channel CavAb with Br-verapamil and in the cryo-EM structure of the Cav1.1 channel with verapamil, the ligands bind in the in...
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Full title
Phenylalkylamines in calcium channels: computational analysis of experimental structures
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TN_cdi_proquest_journals_2449457169
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2449457169
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ISSN
0920-654X
E-ISSN
1573-4951
DOI
10.1007/s10822-020-00330-0
