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Oligonucleotide quantification and metabolite profiling by high-resolution and accurate mass spectro...

Oligonucleotide quantification and metabolite profiling by high-resolution and accurate mass spectro...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2454712813

Oligonucleotide quantification and metabolite profiling by high-resolution and accurate mass spectrometry

About this item

Full title

Oligonucleotide quantification and metabolite profiling by high-resolution and accurate mass spectrometry

Publisher

London: Newlands Press Ltd

Journal title

Bioanalysis, 2019-11, Vol.11 (21), p.1967-1980

Language

English

Formats

Publication information

Publisher

London: Newlands Press Ltd

More information

Scope and Contents

Contents

Advancements in RNA interference therapeutics have triggered development of improved bioanalytical methods for oligonucleotide metabolite profiling and high-throughput quantification in biological matrices.
HPLC coupled with high-resolution mass spectrometry (LC-HRMS) methods were developed to investigate the metabolism of a REVERSIR™ molecule

Alternative Titles

Full title

Oligonucleotide quantification and metabolite profiling by high-resolution and accurate mass spectrometry

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2454712813

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2454712813

Other Identifiers

ISSN

1757-6180

E-ISSN

1757-6199

DOI

10.4155/bio-2019-0137

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