Once-per-week selinexor, bortezomib, and dexamethasone versus twice-per-week bortezomib and dexameth...
Once-per-week selinexor, bortezomib, and dexamethasone versus twice-per-week bortezomib and dexamethasone in patients with multiple myeloma (BOSTON): a randomised, open-label, phase 3 trial
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Author / Creator
Grosicki, Sebastian , Simonova, Maryana , Spicka, Ivan , Pour, Ludek , Kriachok, Iryrna , Gavriatopoulou, Maria , Pylypenko, Halyna , Auner, Holger W , Leleu, Xavier , Doronin, Vadim , Usenko, Ganna , Bahlis, Nizar J , Hajek, Roman , Benjamin, Reuben , Dolai, Tuphan K , Sinha, Dinesh K , Venner, Christopher P , Garg, Mamta , Gironella, Mercedes , Jurczyszyn, Artur , Robak, Pawel , Galli, Monica , Wallington-Beddoe, Craig , Radinoff, Atanas , Salogub, Galina , Stevens, Don A , Basu, Supratik , Liberati, Anna M , Quach, Hang , Goranova-Marinova, Vesselina S , Bila, Jelena , Katodritou, Eirini , Oliynyk, Hanna , Korenkova, Sybiryna , Kumar, Jeevan , Jagannath, Sundar , Moreau, Phillipe , Levy, Moshe , White, Darrell , Gatt, Moshe E , Facon, Thierry , Mateos, Maria V , Cavo, Michele , Reece, Donna , Anderson, Larry D , Saint-Martin, Jean-Richard , Jeha, Jacqueline , Joshi, Anita A , Chai, Yi , Li, Lingling , Peddagali, Vishnuvardhan , Arazy, Melina , Shah, Jatin , Shacham, Sharon , Kauffman, Michael G , Dimopoulos, Meletios A , Richardson, Paul G and Delimpasi, Sosana
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publisher
England: Elsevier Ltd
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More information
Scope and Contents
Contents
Selinexor combined with dexamethasone has shown activity in patients with heavily pre-treated multiple myeloma. In a phase 1b/2 study, the combination of oral selinexor with bortezomib (a proteasome inhibitor) and dexamethasone induced high response rates with low rates of peripheral neuropathy, the main dose-limiting toxicity of bortezomib. We aim...
Alternative Titles
Full title
Once-per-week selinexor, bortezomib, and dexamethasone versus twice-per-week bortezomib and dexamethasone in patients with multiple myeloma (BOSTON): a randomised, open-label, phase 3 trial
Authors, Artists and Contributors
Author / Creator
Simonova, Maryana
Spicka, Ivan
Pour, Ludek
Kriachok, Iryrna
Gavriatopoulou, Maria
Pylypenko, Halyna
Auner, Holger W
Leleu, Xavier
Doronin, Vadim
Usenko, Ganna
Bahlis, Nizar J
Hajek, Roman
Benjamin, Reuben
Dolai, Tuphan K
Sinha, Dinesh K
Venner, Christopher P
Garg, Mamta
Gironella, Mercedes
Jurczyszyn, Artur
Robak, Pawel
Galli, Monica
Wallington-Beddoe, Craig
Radinoff, Atanas
Salogub, Galina
Stevens, Don A
Basu, Supratik
Liberati, Anna M
Quach, Hang
Goranova-Marinova, Vesselina S
Bila, Jelena
Katodritou, Eirini
Oliynyk, Hanna
Korenkova, Sybiryna
Kumar, Jeevan
Jagannath, Sundar
Moreau, Phillipe
Levy, Moshe
White, Darrell
Gatt, Moshe E
Facon, Thierry
Mateos, Maria V
Cavo, Michele
Reece, Donna
Anderson, Larry D
Saint-Martin, Jean-Richard
Jeha, Jacqueline
Joshi, Anita A
Chai, Yi
Li, Lingling
Peddagali, Vishnuvardhan
Arazy, Melina
Shah, Jatin
Shacham, Sharon
Kauffman, Michael G
Dimopoulos, Meletios A
Richardson, Paul G
Delimpasi, Sosana
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2460043998
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2460043998
Other Identifiers
ISSN
0140-6736
E-ISSN
1474-547X
DOI
10.1016/S0140-6736(20)32292-3
