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Venetoclax for chronic lymphocytic leukaemia progressing after ibrutinib: an interim analysis of a m...

Venetoclax for chronic lymphocytic leukaemia progressing after ibrutinib: an interim analysis of a m...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2465717830

Venetoclax for chronic lymphocytic leukaemia progressing after ibrutinib: an interim analysis of a multicentre, open-label, phase 2 trial

About this item

Full title

Venetoclax for chronic lymphocytic leukaemia progressing after ibrutinib: an interim analysis of a multicentre, open-label, phase 2 trial

Publisher

England: Elsevier Ltd

Journal title

The lancet oncology, 2018, Vol.19 (1), p.65-75

Language

English

Formats

Publication information

Publisher

England: Elsevier Ltd

Subjects

Subjects and topics

More information

Scope and Contents

Contents

SummaryBackgroundTherapy targeting Bruton's tyrosine kinase (BTK) with ibrutinib has transformed the treatment of chronic lymphocytic leukaemia. However, patients who are refractory to or relapse after ibrutinib therapy have poor outcomes. Venetoclax is a selective, orally bioavailable inhibitor of BCL-2 active in previously treated patients with r...

Alternative Titles

Full title

Venetoclax for chronic lymphocytic leukaemia progressing after ibrutinib: an interim analysis of a multicentre, open-label, phase 2 trial

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2465717830

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2465717830

Other Identifiers

ISSN

1470-2045

E-ISSN

1474-5488

DOI

10.1016/S1470-2045(17)30909-9

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