Structural and functional characterization of M. tuberculosis sedoheptulose- 7-phosphate isomerase,...
Structural and functional characterization of M. tuberculosis sedoheptulose- 7-phosphate isomerase, a critical enzyme involved in lipopolysaccharide biosynthetic pathway
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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M. tuberculosis
GmhA enzyme catalyzes the isomerization of D-sedoheptulose 7-phosphate into D-glycero-D-α-manno-heptose-7-phosphate in GDP-D-glycero-α-D-manno-heptose biosynthetic pathway. The D-glycero-α-D-manno-heptose is a major constituent of lipopolysaccharide and contributes to virulence and antibiotic resistance to mycobacteria. In curren...
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Structural and functional characterization of M. tuberculosis sedoheptulose- 7-phosphate isomerase, a critical enzyme involved in lipopolysaccharide biosynthetic pathway
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TN_cdi_proquest_journals_2473271108
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2473271108
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ISSN
2045-2322
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2045-2322
DOI
10.1038/s41598-020-77230-8