SDHA gain-of-function engages inflammatory mitochondrial retrograde signaling via KEAP1–Nrf2
SDHA gain-of-function engages inflammatory mitochondrial retrograde signaling via KEAP1–Nrf2
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Author / Creator
Burgener, Anne-Valérie , Bantug, Glenn R. , Meyer, Benedikt J. , Higgins, Rebecca , Ghosh, Adhideb , Bignucolo, Olivier , Ma, Eric H. , Loeliger, Jordan , Unterstab, Gunhild , Geigges, Marco , Steiner, Rebekah , Enamorado, Michel , Ivanek, Robert , Hunziker, Danielle , Schmidt, Alexander , Müller-Durovic, Bojana , Grählert, Jasmin , Epple, Raja , Dimeloe, Sarah , Lötscher, Jonas , Sauder, Ursula , Ebnöther, Monika , Burger, Bettina , Heijnen, Ingmar , Martínez-Cano, Sarai , Cantoni, Nathan , Brücker, Rolf , Kahlert, Christian R. , Sancho, David , Jones, Russell G. , Navarini, Alexander , Recher, Mike and Hess, Christoph
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Whether screening the metabolic activity of immune cells facilitates discovery of molecular pathology remains unknown. Here we prospectively screened the extracellular acidification rate as a measure of glycolysis and the oxygen consumption rate as a measure of mitochondrial respiration in B cells from patients with primary antibody deficiency. The...
Alternative Titles
Full title
SDHA gain-of-function engages inflammatory mitochondrial retrograde signaling via KEAP1–Nrf2
Authors, Artists and Contributors
Author / Creator
Bantug, Glenn R.
Meyer, Benedikt J.
Higgins, Rebecca
Ghosh, Adhideb
Bignucolo, Olivier
Ma, Eric H.
Loeliger, Jordan
Unterstab, Gunhild
Geigges, Marco
Steiner, Rebekah
Enamorado, Michel
Ivanek, Robert
Hunziker, Danielle
Schmidt, Alexander
Müller-Durovic, Bojana
Grählert, Jasmin
Epple, Raja
Dimeloe, Sarah
Lötscher, Jonas
Sauder, Ursula
Ebnöther, Monika
Burger, Bettina
Heijnen, Ingmar
Martínez-Cano, Sarai
Cantoni, Nathan
Brücker, Rolf
Kahlert, Christian R.
Sancho, David
Jones, Russell G.
Navarini, Alexander
Recher, Mike
Hess, Christoph
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Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2474981476
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2474981476
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-019-0482-2