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The dose threshold for nanoparticle tumour delivery

The dose threshold for nanoparticle tumour delivery

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2475010857

The dose threshold for nanoparticle tumour delivery

About this item

Full title

The dose threshold for nanoparticle tumour delivery

Publisher

London: Nature Publishing Group UK

Journal title

Nature materials, 2020-12, Vol.19 (12), p.1362-1371

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Nanoparticle delivery to solid tumours over the past ten years has stagnated at a median of 0.7% of the injected dose. Varying nanoparticle designs and strategies have yielded only minor improvements. Here we discovered a dose threshold for improving nanoparticle tumour delivery: 1 trillion nanoparticles in mice. Doses above this threshold overwhel...

Alternative Titles

Full title

The dose threshold for nanoparticle tumour delivery

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2475010857

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2475010857

Other Identifiers

ISSN

1476-1122

E-ISSN

1476-4660

DOI

10.1038/s41563-020-0755-z

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