p21CIP1 controls the squamous differentiation response to replication stress
p21CIP1 controls the squamous differentiation response to replication stress
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Publisher
London: Nature Publishing Group UK
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Language
English
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Publisher
London: Nature Publishing Group UK
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Contents
The control of cell fate is critical to homeostasis and cancer. Cell cycle cdk inhibitor p21CIP1 has a central and paradoxical role in the regulatory crossroads leading to senescence, apoptosis, or differentiation. p21 is an essential target of tumor suppressor p53, but it also is regulated independently. In squamous self-renewal epithelia continuo...
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Full title
p21CIP1 controls the squamous differentiation response to replication stress
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TN_cdi_proquest_journals_2476057089
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2476057089
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-020-01520-8
