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Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to h...

Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to h...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2476251403

Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression

About this item

Full title

Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression

Publisher

London: Nature Publishing Group UK

Journal title

Nature cell biology, 2021-01, Vol.23 (1), p.87-98

Language

English

Formats

Publication information

Publisher

London: Nature Publishing Group UK

More information

Scope and Contents

Contents

Prostate cancer shows remarkable clinical heterogeneity, which manifests in spatial and clonal genomic diversity. By contrast, the transcriptomic heterogeneity of prostate tumours is poorly understood. Here we have profiled the transcriptomes of 36,424 single cells from 13 prostate tumours and identified the epithelial cells underlying disease aggr...

Alternative Titles

Full title

Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2476251403

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2476251403

Other Identifiers

ISSN

1465-7392

E-ISSN

1476-4679

DOI

10.1038/s41556-020-00613-6

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