Hypermethylation of FOXA1 and allelic loss of PTEN drive squamous differentiation and promote hetero...
Hypermethylation of FOXA1 and allelic loss of PTEN drive squamous differentiation and promote heterogeneity in bladder cancer
About this item
Full title
Author / Creator
Osei-Amponsa, Vasty , Buckwalter, Jenna M. , Shuman, Lauren , Zheng, Zongyu , Yamashita, Hironobu , Walter, Vonn , Wildermuth, Thomas , Ellis-Mohl, Justine , Liu, Chang , Warrick, Joshua I. , Shantz, Lisa M. , Feehan, Robert P. , Al-Ahmadie, Hikmat , Mendelsohn, Cathy , Raman, Jay D. , Kaestner, Klaus H. , Wu, Xue-Ru and DeGraff, David J.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
Intratumoral heterogeneity in bladder cancer is a barrier to accurate molecular sub-classification and treatment efficacy. However, individual cellular and mechanistic contributions to tumor heterogeneity are controversial. We examined potential mechanisms of
FOXA1
and
PTEN
inactivation in bladder cancer and their contribution to tumor...
Alternative Titles
Full title
Hypermethylation of FOXA1 and allelic loss of PTEN drive squamous differentiation and promote heterogeneity in bladder cancer
Authors, Artists and Contributors
Author / Creator
Buckwalter, Jenna M.
Shuman, Lauren
Zheng, Zongyu
Yamashita, Hironobu
Walter, Vonn
Wildermuth, Thomas
Ellis-Mohl, Justine
Liu, Chang
Warrick, Joshua I.
Shantz, Lisa M.
Feehan, Robert P.
Al-Ahmadie, Hikmat
Mendelsohn, Cathy
Raman, Jay D.
Kaestner, Klaus H.
Wu, Xue-Ru
DeGraff, David J.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2476735892
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2476735892
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-019-1063-4
