Histone deacetylases, Mbd3/NuRD, and Tet2 hydroxylase are crucial regulators of epithelial–mesenchym...
Histone deacetylases, Mbd3/NuRD, and Tet2 hydroxylase are crucial regulators of epithelial–mesenchymal plasticity and tumor metastasis
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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An epithelial–mesenchymal transition (EMT) represents a basic morphogenetic process of high cell plasticity underlying embryogenesis, wound healing, cancer metastasis and drug resistance. It involves a profound transcriptional and epigenetic reprogramming of cells. A critical role of epigenetic modifiers and their specific chromatin modifications h...
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Histone deacetylases, Mbd3/NuRD, and Tet2 hydroxylase are crucial regulators of epithelial–mesenchymal plasticity and tumor metastasis
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TN_cdi_proquest_journals_2476736323
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2476736323
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-019-1081-2
