Targeted, random mutagenesis of plant genes with dual cytosine and adenine base editors
Targeted, random mutagenesis of plant genes with dual cytosine and adenine base editors
About this item
Full title
Author / Creator
Li, Chao , Zhang, Rui , Meng, Xiangbing , Chen, Sha , Zong, Yuan , Lu, Chunju , Qiu, Jin-Long , Chen, Yu-Hang , Li, Jiayang and Gao, Caixia
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
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More information
Scope and Contents
Contents
Targeted saturation mutagenesis of crop genes could be applied to produce genetic variants with improved agronomic performance. However, tools for directed evolution of plant genes, such as error-prone PCR or DNA shuffling, are limited
1
. We engineered five saturated targeted endogenous mutagenesis editors (STEMEs) that can generate de novo...
Alternative Titles
Full title
Targeted, random mutagenesis of plant genes with dual cytosine and adenine base editors
Authors, Artists and Contributors
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Record Identifier
TN_cdi_proquest_journals_2476758532
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2476758532
Other Identifiers
ISSN
1087-0156
E-ISSN
1546-1696
DOI
10.1038/s41587-019-0393-7
