Distinct co-acquired alterations and genomic evolution during TKI treatment in non-small-cell lung c...
Distinct co-acquired alterations and genomic evolution during TKI treatment in non-small-cell lung cancer patients with or without acquired T790M mutation
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Author / Creator
Jin, Ying , Bao, Hua , Le, Xiuning , Fan, Xiaojun , Tang, Ming , Shi, Xun , Zhao, Jun , Yan, Junrong , Xu, Yang , Quek, Kelly , Elamin, Yasir Y. , Zhang, Jianhua , Futreal, P. Andrew , Wistuba, Ignacio I. , Heymach, John V. , Lou, Guangyuan , Shao, Lan , He, Qiong , Lin, Chen , Wu, Xue , Shao, Yang W. , Wang, Xiaonan , He, Jiachen , Chen, Yamei , Stebbing, Justin , Chen, Ming , Zhang, Jianjun and Yu, Xinmin
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
EGFR
-mutant non-small-cell lung cancer (NSCLC) patients inevitably develop drug resistance when treated with EGFR tyrosine kinase inhibitors (TKIs). Systematic genetic analysis is important to understand drug-resistant mechanisms; however, the clinical significance of co-occurring genetic alterations at baseline, co-acquired mutations at progre...
Alternative Titles
Full title
Distinct co-acquired alterations and genomic evolution during TKI treatment in non-small-cell lung cancer patients with or without acquired T790M mutation
Authors, Artists and Contributors
Author / Creator
Bao, Hua
Le, Xiuning
Fan, Xiaojun
Tang, Ming
Shi, Xun
Zhao, Jun
Yan, Junrong
Xu, Yang
Quek, Kelly
Elamin, Yasir Y.
Zhang, Jianhua
Futreal, P. Andrew
Wistuba, Ignacio I.
Heymach, John V.
Lou, Guangyuan
Shao, Lan
He, Qiong
Lin, Chen
Wu, Xue
Shao, Yang W.
Wang, Xiaonan
He, Jiachen
Chen, Yamei
Stebbing, Justin
Chen, Ming
Zhang, Jianjun
Yu, Xinmin
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2476769847
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2476769847
Other Identifiers
ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-019-1104-z
