Clioquinol inhibits dopamine-β-hydroxylase secretion and noradrenaline synthesis by affecting the re...
Clioquinol inhibits dopamine-β-hydroxylase secretion and noradrenaline synthesis by affecting the redox status of ATOX1 and copper transport in human neuroblastoma SH-SY5Y cells
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Berlin/Heidelberg: Springer Berlin Heidelberg
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English
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Berlin/Heidelberg: Springer Berlin Heidelberg
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Clioquinol (5-chloro-7-indo-8-quinolinol), a chelator and ionophore of copper/zinc, was extensively used as an amebicide to treat indigestion and diarrhea in the mid-1900s. However, it was withdrawn from the market in Japan because its use was epidemiologically linked to an increase in the incidence of subacute myelo-optic neuropathy (SMON). SMON i...
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Full title
Clioquinol inhibits dopamine-β-hydroxylase secretion and noradrenaline synthesis by affecting the redox status of ATOX1 and copper transport in human neuroblastoma SH-SY5Y cells
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TN_cdi_proquest_journals_2478285369
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2478285369
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ISSN
0340-5761,1432-0738
E-ISSN
1432-0738
DOI
10.1007/s00204-020-02894-0
