Efficient Synthesis of Pharmaceutically Relevant Prochiral Heterocyclic Aminoketones
Efficient Synthesis of Pharmaceutically Relevant Prochiral Heterocyclic Aminoketones
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Budapest: Periodica Polytechnica, Budapest University of Technology and Economics
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English
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Budapest: Periodica Polytechnica, Budapest University of Technology and Economics
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In this work, we report a practical method for alkylation of saturated heterocycles with chloroacetone yielding prochiral heterocyclic ketones, including previously not described molecules. The desired building blocks were obtained with high yields in hydrochloric salt forms, without the need for chromatographic purification.
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Efficient Synthesis of Pharmaceutically Relevant Prochiral Heterocyclic Aminoketones
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TN_cdi_proquest_journals_2495228848
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2495228848
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ISSN
0324-5853
E-ISSN
1587-3765
DOI
10.3311/PPch.16489
