Pasotuxizumab, a Bite ® Immune Therapy for Castration-Resistant Prostate Cancer: Phase I, Dose-Escal...
Pasotuxizumab, a Bite ® Immune Therapy for Castration-Resistant Prostate Cancer: Phase I, Dose-Escalation Study Findings
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Author / Creator
Hummel, Horst-Dieter , Kufer, Peter , Grüllich, Carsten , Seggewiss-Bernhardt, Ruth , Deschler-Baier, Barbara , Chatterjee, Manik , Goebeler, Maria-Elisabeth , Miller, Kurt , de Santis, Maria , Loidl, Wolfgang , Dittrich, Christian , Buck, Andreas , Lapa, Constantin , Thurner, Annette , Wittemer-Rump, Sabine , Koca, Gökben , Boix, Oliver , Döcke, Wolf-Dietrich , Finnern, Ricarda , Kusi, Helena , Ajavon-Hartmann, Antoinette , Stienen, Sabine , Sayehli, Cyrus Michael , Polat, Bülent and Bargou, Ralf C
Publisher
London: Future Medicine Ltd
Journal title
Language
English
Formats
Publication information
Publisher
London: Future Medicine Ltd
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More information
Scope and Contents
Contents
Aim: We report results of a first-in-human study of pasotuxizumab, a PSMA bispecific T-cell engager (BiTE®) immune therapy mediating T-cell killing of tumor cells in patients with advanced castration-resistant prostate cancer. Patients & methods: We assessed once-daily subcutaneous (SC) pasotuxizumab. All SC patients developed antidrug antibodies;...
Alternative Titles
Full title
Pasotuxizumab, a Bite ® Immune Therapy for Castration-Resistant Prostate Cancer: Phase I, Dose-Escalation Study Findings
Authors, Artists and Contributors
Author / Creator
Kufer, Peter
Grüllich, Carsten
Seggewiss-Bernhardt, Ruth
Deschler-Baier, Barbara
Chatterjee, Manik
Goebeler, Maria-Elisabeth
Miller, Kurt
de Santis, Maria
Loidl, Wolfgang
Dittrich, Christian
Buck, Andreas
Lapa, Constantin
Thurner, Annette
Wittemer-Rump, Sabine
Koca, Gökben
Boix, Oliver
Döcke, Wolf-Dietrich
Finnern, Ricarda
Kusi, Helena
Ajavon-Hartmann, Antoinette
Stienen, Sabine
Sayehli, Cyrus Michael
Polat, Bülent
Bargou, Ralf C
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2501458773
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2501458773
Other Identifiers
ISSN
1750-743X
E-ISSN
1750-7448
DOI
10.2217/imt-2020-0256
