Tumor-derived osteopontin drives the resident fibroblast to myofibroblast differentiation through Tw...
Tumor-derived osteopontin drives the resident fibroblast to myofibroblast differentiation through Twist1 to promote breast cancer progression
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London: Nature Publishing Group UK
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English
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London: Nature Publishing Group UK
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Tumor-stroma interactions are important determinants for the disease course in cancer. While stromal influence has been known to often play a tumor-promoting role, incomplete mechanistic insight into this phenomenon has prevented its therapeutic targeting. Stromal fibroblasts can be activated by tumor cells to differentiate into cancer-associated f...
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Full title
Tumor-derived osteopontin drives the resident fibroblast to myofibroblast differentiation through Twist1 to promote breast cancer progression
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TN_cdi_proquest_journals_2503047477
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2503047477
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ISSN
0950-9232
E-ISSN
1476-5594
DOI
10.1038/s41388-021-01663-2
