Aurora kinase inhibition sensitizes melanoma cells to T-cell-mediated cytotoxicity
Aurora kinase inhibition sensitizes melanoma cells to T-cell-mediated cytotoxicity
About this item
Full title
Author / Creator
Punt, Simone , Malu, Shruti , McKenzie, Jodi A. , Manrique, Soraya Zorro , Doorduijn, Elien M. , Mbofung, Rina M. , Williams, Leila , Silverman, Deborah A. , Ashkin, Emily L. , Dominguez, Ana Lucía , Wang, Zhe , Chen, Jie Qing , Maiti, Sourindra N. , Tieu, Trang N. , Liu, Chengwen , Xu, Chunyu , Forget, Marie-Andrée , Haymaker, Cara , Khalili, Jahan S. , Satani, Nikunj , Muller, Florian , Cooper, Laurence J. N. , Overwijk, Willem W. , Amaria, Rodabe N. , Bernatchez, Chantale , Heffernan, Timothy P. , Peng, Weiyi , Roszik, Jason and Hwu, Patrick
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title
Language
English
Formats
Publication information
Publisher
Berlin/Heidelberg: Springer Berlin Heidelberg
Subjects
More information
Scope and Contents
Contents
Although immunotherapy has achieved impressive durable clinical responses, many cancers respond only temporarily or not at all to immunotherapy. To find novel, targetable mechanisms of resistance to immunotherapy, patient-derived melanoma cell lines were transduced with 576 open reading frames, or exposed to arrayed libraries of 850 bioactive compo...
Alternative Titles
Full title
Aurora kinase inhibition sensitizes melanoma cells to T-cell-mediated cytotoxicity
Authors, Artists and Contributors
Author / Creator
Malu, Shruti
McKenzie, Jodi A.
Manrique, Soraya Zorro
Doorduijn, Elien M.
Mbofung, Rina M.
Williams, Leila
Silverman, Deborah A.
Ashkin, Emily L.
Dominguez, Ana Lucía
Wang, Zhe
Chen, Jie Qing
Maiti, Sourindra N.
Tieu, Trang N.
Liu, Chengwen
Xu, Chunyu
Forget, Marie-Andrée
Haymaker, Cara
Khalili, Jahan S.
Satani, Nikunj
Muller, Florian
Cooper, Laurence J. N.
Overwijk, Willem W.
Amaria, Rodabe N.
Bernatchez, Chantale
Heffernan, Timothy P.
Peng, Weiyi
Roszik, Jason
Hwu, Patrick
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2503048672
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2503048672
Other Identifiers
ISSN
0340-7004,1432-0851
E-ISSN
1432-0851
DOI
10.1007/s00262-020-02748-9