PRSS2 stimulates tumor growth by remodeling the TME via repression of Tsp1
PRSS2 stimulates tumor growth by remodeling the TME via repression of Tsp1
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Author / Creator
Lufei Sui , Wang, Suming , Ganguly, Debolina , Tina El Rayes , Askeland, Cecilie , Borretzen, Astrid , Zhou, Kun , Sim, Danielle , Halvorsen, Ole Johan , Knutsvik, Goril , Aziz, Sura , Haukaas, Svein , Foulkes, William D , Bielenberg, Diane R , Ziemys, Arturas , Mittall, Vivek , Brekken, Rolf A , Akslen, Lars A and Watnick, Randolph S
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Contents
In the earliest stages of tumor development, epithelial tumors (carcinomas) are physically confined to the area of the tissue in which they form. These nascent lesions (carcinomas in situ) are sequestered from the tissue parenchyma by the basement membrane. Within the tissue parenchyma lie a myriad of cell types comprised of fibroblasts, immune and...
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Full title
PRSS2 stimulates tumor growth by remodeling the TME via repression of Tsp1
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TN_cdi_proquest_journals_2504850173
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2504850173
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E-ISSN
2692-8205
DOI
10.1101/2021.03.23.436667
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https://www.proquest.com/docview/2504850173?pq-origsite=primo&accountid=13902
