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MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin...

MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2504874745

MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior

About this item

Full title

MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-03

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Abstract MDGAs are molecules that can bind neuroligins in cis and interfere with trans-synaptic neurexin-neuroligin interactions, thereby impairing synapse development. However, the sub-cellular localization and dynamics of MDGAs, as well as their specific mode of action in neurons are still unclear. Here, using both surface immunostaining of endog...

Alternative Titles

Full title

MDGAs are fast-diffusing molecules that delay excitatory synapse development by altering neuroligin behavior

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2504874745

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2504874745

Other Identifiers

ISSN

2692-8205

E-ISSN

2692-8205

DOI

10.1101/2021.03.16.435652

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