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Elevated N-glycosylation of immunoglobulin G variable regions in myasthenia gravis highlights a comm...

Elevated N-glycosylation of immunoglobulin G variable regions in myasthenia gravis highlights a comm...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2504961995

Elevated N-glycosylation of immunoglobulin G variable regions in myasthenia gravis highlights a commonality across autoantibody-associated diseases

About this item

Full title

Elevated N-glycosylation of immunoglobulin G variable regions in myasthenia gravis highlights a commonality across autoantibody-associated diseases

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-03

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Abstract Elevated N-linked glycosylation of immunoglobulin G variable regions (IgG-VN-Glyc) is an emerging molecular phenotype associated with autoimmune disorders. To test the broader specificity of elevated IgG-VN-Glyc, we studied patients with distinct subtypes of myasthenia gravis (MG), a B cell-mediated autoimmune disease. Our experimental des...

Alternative Titles

Full title

Elevated N-glycosylation of immunoglobulin G variable regions in myasthenia gravis highlights a commonality across autoantibody-associated diseases

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2504961995

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2504961995

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.03.06.434199