Intracellular sterol sensing controls intestinal B cell differentiation
Intracellular sterol sensing controls intestinal B cell differentiation
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Abstract Intestinal B cell responses are critical for the maintenance of gut homeostasis, yet environmental signals that control B cell metabolism and effector function remain poorly characterized. Here, we show that Peyer’s patches germinal center (GC) B cells are sensitive to 25-hydroxycholesterol (25-HC), an oxidized metabolite of cholesterol pr...
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Full title
Intracellular sterol sensing controls intestinal B cell differentiation
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TN_cdi_proquest_journals_2504968718
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2504968718
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E-ISSN
2692-8205
DOI
10.1101/2020.11.03.367177
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https://www.proquest.com/docview/2504968718?pq-origsite=primo&accountid=13902
