FGFR inhibitor mediated dismissal of SWI/SNF complexes from YAP-dependent enhancers induces adaptive...
FGFR inhibitor mediated dismissal of SWI/SNF complexes from YAP-dependent enhancers induces adaptive therapeutic resistance
About this item
Full title
Author / Creator
Li, Yihao , Qiu, Xintao , Wang, Xiaoqing , Liu, Hui , Geck, Renee C , Tewari, Alok K , Xiao, Tengfei , Font-Tello, Alba , Lim, Klothilda , Jones, Kristen L , Morrow, Murry , Vadhi, Raga , Pei-Lun Kao , Jaber, Aliya , Yerrum, Smitha , Xie, Yingtian , Kin-Hoe Chow , Cejas, Paloma , Nguyen, Quang-Dé , Long, Henry W , X Shirley Liu , Toker, Alex and Brown, Myles
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
Formats
Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Subjects
More information
Scope and Contents
Contents
Abstract How cancer cells adapt to evade the therapeutic effects of drugs targeting oncogenic drivers is poorly understood. Here we report an epigenetic mechanism leading to the adaptive resistance of triple-negative breast cancer (TNBC) to fibroblast growth factor receptor (FGFR) inhibitors. Prolonged FGFR inhibition suppresses the function of BRG...
Alternative Titles
Full title
FGFR inhibitor mediated dismissal of SWI/SNF complexes from YAP-dependent enhancers induces adaptive therapeutic resistance
Authors, Artists and Contributors
Author / Creator
Qiu, Xintao
Wang, Xiaoqing
Liu, Hui
Geck, Renee C
Tewari, Alok K
Xiao, Tengfei
Font-Tello, Alba
Lim, Klothilda
Jones, Kristen L
Morrow, Murry
Vadhi, Raga
Pei-Lun Kao
Jaber, Aliya
Yerrum, Smitha
Xie, Yingtian
Kin-Hoe Chow
Cejas, Paloma
Nguyen, Quang-Dé
Long, Henry W
X Shirley Liu
Toker, Alex
Brown, Myles
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2505133996
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2505133996
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2021.03.02.433446
How to access this item
https://www.proquest.com/docview/2505133996?pq-origsite=primo&accountid=13902
