Targeted replacement of full-length CFTR in human airway stem cells by CRISPR/Cas9 for pan-mutation...
Targeted replacement of full-length CFTR in human airway stem cells by CRISPR/Cas9 for pan-mutation correction in the endogenous locus
About this item
Full title
Author / Creator
Vaidyanathan, Sriram , Baik, Ron , Chen, Lu , Bravo, Dawn T , Suarez, Carlos J , Abazari, Shayda M , Salahudeen, Ameen A , Dudek, Amanda M , Teran, Christopher A , Davis, Timothy H , Lee, Ciaran M , Bao, Gang , Randell, Scott H , Artandi, Steven E , Wine, Jeffrey J , Kuo, Calvin J , Desai, Tushar J , Nayak, Jayakar V , Sellers, Zachary M and Porteus, Matthew H
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
Formats
Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Subjects
More information
Scope and Contents
Contents
Abstract Cystic fibrosis (CF) is a monogenic disease caused by impaired production and/or function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein. Although we have previously shown correction of the most common pathogenic mutation, there are many other pathogenic mutations throughout the CF gene. An autologous airway stem...
Alternative Titles
Full title
Targeted replacement of full-length CFTR in human airway stem cells by CRISPR/Cas9 for pan-mutation correction in the endogenous locus
Authors, Artists and Contributors
Author / Creator
Baik, Ron
Chen, Lu
Bravo, Dawn T
Suarez, Carlos J
Abazari, Shayda M
Salahudeen, Ameen A
Dudek, Amanda M
Teran, Christopher A
Davis, Timothy H
Lee, Ciaran M
Bao, Gang
Randell, Scott H
Artandi, Steven E
Wine, Jeffrey J
Kuo, Calvin J
Desai, Tushar J
Nayak, Jayakar V
Sellers, Zachary M
Porteus, Matthew H
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2505394841
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2505394841
Other Identifiers
ISSN
2692-8205
E-ISSN
2692-8205
DOI
10.1101/2021.02.26.432961
