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Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynami...

Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynami...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2505438790

Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynamic wave

About this item

Full title

Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynamic wave

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-02

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Abstract Microglia, the brain’s resident myeloid cells, play central roles in brain defense, homeostasis, and disease. Using sustained colony-stimulating factor 1 receptor inhibition, we report an unprecedented level of microglial depletion and establish a model system that achieves an empty microglial niche in the adult brain. We identify a myeloi...

Alternative Titles

Full title

Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynamic wave

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2505438790

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2505438790

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.02.17.431594