Improving antibody thermostability based on statistical analysis of sequence and structural consensu...
Improving antibody thermostability based on statistical analysis of sequence and structural consensus data
About this item
Full title
Author / Creator
Jia, Lei , Jain, Mani and Sun, Yaxiong
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
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Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Scope and Contents
Contents
Abstract The use of Monoclonal Antibodies (MAbs) as therapeutics has been increasing over the past 30 years due to their high specificity and strong affinity towards the target. One of the major challenges towards their use as drugs is their low thermostability, which impacts both efficacy as well as manufacturing and delivery. To aid the design of...
Alternative Titles
Full title
Improving antibody thermostability based on statistical analysis of sequence and structural consensus data
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Author / Creator
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Record Identifier
TN_cdi_proquest_journals_2505704756
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2505704756
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2021.01.28.428721
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https://www.proquest.com/docview/2505704756?pq-origsite=primo&accountid=13902
