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GLS-driven glutamine catabolism contributes to prostate cancer radiosensitivity by regulating the re...

GLS-driven glutamine catabolism contributes to prostate cancer radiosensitivity by regulating the re...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2505887127

GLS-driven glutamine catabolism contributes to prostate cancer radiosensitivity by regulating the redox state, stemness and ATG5-mediated autophagy

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Abstract Radiotherapy is one of the curative treatment options for localized prostate cancer (PCa). The curative potential of radiotherapy is mediated by irradiation-induced oxidative stress and DNA damage in tumor cells. However, PCa radiocurability can be impeded by tumor resistance mechanisms and normal tissue toxicity. Metabolic reprogramming i...

Alternative Titles

Full title

GLS-driven glutamine catabolism contributes to prostate cancer radiosensitivity by regulating the redox state, stemness and ATG5-mediated autophagy

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2505887127

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2505887127

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.01.07.425771