Lysosomal retargeting of Myoferlin mitigates membrane stress to enable pancreatic cancer growth
Lysosomal retargeting of Myoferlin mitigates membrane stress to enable pancreatic cancer growth
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Abstract Lysosomes must maintain integrity of their limiting membrane to ensure efficient fusion with incoming organelles and degradation of substrates within their lumen. Pancreatic cancer cells upregulate lysosomal biogenesis to enhance nutrient recycling and stress resistance, but whether dedicated programs for maintaining lysosomal membrane int...
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Full title
Lysosomal retargeting of Myoferlin mitigates membrane stress to enable pancreatic cancer growth
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TN_cdi_proquest_journals_2505887486
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2505887486
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E-ISSN
2692-8205
DOI
10.1101/2021.01.04.425106
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https://www.proquest.com/docview/2505887486?pq-origsite=primo&accountid=13902