Single cell proteomics of tumor compartments identifies differential kinase activities defining sens...
Single cell proteomics of tumor compartments identifies differential kinase activities defining sensitivity to mTOR-PI3-kinase inhibition
About this item
Full title
Author / Creator
Karabacak, Nezihi Murat , Zheng, Yu , Dubash, Taronish D , Burr, Risa , Micalizzi, Douglas S , Wittner, Ben S , Wiley, Devon , Valentine Comaills , Emmons, Erin , Niederhoffer, Kira , Ho, Uyen , Nieman, Linda , Haas, Wilhelm , Stott, Shannon L , Ting, David T , Miyamoto, David T , Haber, Daniel A , Toner, Mehmet and Maheswaran, Shyamala
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
Formats
Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Subjects
More information
Scope and Contents
Contents
ABSTRACT Cancer therapy often results in heterogeneous responses in different metastatic lesions in the same patient. Inter- and intra-tumor heterogeneity in proteomic signaling within the various tumor compartments and its impact on therapy are not well characterized due to the limited sensitivity of single cell proteomic approaches. To overcome t...
Alternative Titles
Full title
Single cell proteomics of tumor compartments identifies differential kinase activities defining sensitivity to mTOR-PI3-kinase inhibition
Authors, Artists and Contributors
Author / Creator
Zheng, Yu
Dubash, Taronish D
Burr, Risa
Micalizzi, Douglas S
Wittner, Ben S
Wiley, Devon
Valentine Comaills
Emmons, Erin
Niederhoffer, Kira
Ho, Uyen
Nieman, Linda
Haas, Wilhelm
Stott, Shannon L
Ting, David T
Miyamoto, David T
Haber, Daniel A
Toner, Mehmet
Maheswaran, Shyamala
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2505887582
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2505887582
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2021.01.06.425147
How to access this item
https://www.proquest.com/docview/2505887582?pq-origsite=primo&accountid=13902
