Log in to save to my catalogue

The molecular principles of Piwi-mediated co-transcriptional silencing through the dimeric SFiNX com...

The molecular principles of Piwi-mediated co-transcriptional silencing through the dimeric SFiNX com...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2505887585

The molecular principles of Piwi-mediated co-transcriptional silencing through the dimeric SFiNX complex

About this item

Full title

The molecular principles of Piwi-mediated co-transcriptional silencing through the dimeric SFiNX complex

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-01

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Abstract Nuclear Argonaute proteins, guided to nascent target RNAs by their bound small RNAs, elicit co-transcriptional silencing through heterochromatin formation at transposon insertions and repetitive genomic loci. The molecular mechanisms involved in this process are incompletely understood. Here, we propose that the SFiNX complex, a silencing...

Alternative Titles

Full title

The molecular principles of Piwi-mediated co-transcriptional silencing through the dimeric SFiNX complex

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2505887585

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2505887585

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.01.08.425619