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Human B cell lineages engaged by germinal centers following influenza vaccination are measurably evo...

Human B cell lineages engaged by germinal centers following influenza vaccination are measurably evo...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2505888462

Human B cell lineages engaged by germinal centers following influenza vaccination are measurably evolving

About this item

Full title

Human B cell lineages engaged by germinal centers following influenza vaccination are measurably evolving

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-01

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

Abstract Poor efficacy of seasonal influenza virus vaccines is often attributed to pre-existing immunity interfering with the persistence and maturation of vaccine-induced B cell responses.1 Consistent with this notion, no significant increase in somatic hypermutation (SHM) among circulating influenza-binding lineages was detected following seasona...

Alternative Titles

Full title

Human B cell lineages engaged by germinal centers following influenza vaccination are measurably evolving

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2505888462

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2505888462

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.01.06.425648