Human B cell lineages engaged by germinal centers following influenza vaccination are measurably evo...
Human B cell lineages engaged by germinal centers following influenza vaccination are measurably evolving
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Abstract Poor efficacy of seasonal influenza virus vaccines is often attributed to pre-existing immunity interfering with the persistence and maturation of vaccine-induced B cell responses.1 Consistent with this notion, no significant increase in somatic hypermutation (SHM) among circulating influenza-binding lineages was detected following seasona...
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Human B cell lineages engaged by germinal centers following influenza vaccination are measurably evolving
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TN_cdi_proquest_journals_2505888462
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2505888462
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E-ISSN
2692-8205
DOI
10.1101/2021.01.06.425648
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https://www.proquest.com/docview/2505888462?pq-origsite=primo&accountid=13902