Allele-specific endogenous tagging and quantitative analysis of beta-catenin in colorectal cancer ce...
Allele-specific endogenous tagging and quantitative analysis of beta-catenin in colorectal cancer cells
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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Language
English
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Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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ABSTRACT Wnt signaling plays important roles in development, homeostasis, and tumorigenesis. Mutations in β-catenin that activate Wnt signaling have been found in colorectal and hepatocellular carcinomas. However, the dynamics of wild-type and mutant forms of β-catenin are not fully understood. Here, we genome-engineered fluorescently tagged allele...
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Full title
Allele-specific endogenous tagging and quantitative analysis of beta-catenin in colorectal cancer cells
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TN_cdi_proquest_journals_2506025021
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2506025021
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E-ISSN
2692-8205
DOI
10.1101/2020.06.18.159616
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https://www.proquest.com/docview/2506025021?pq-origsite=primo&accountid=13902
