An immunogenic model of KRAS-mutant lung cancer for study of targeted therapy and immunotherapy comb...
An immunogenic model of KRAS-mutant lung cancer for study of targeted therapy and immunotherapy combinations
About this item
Full title
Author / Creator
Boumelha, Jesse , Sophie De Carne Trecesson , Law, Emily , Romero-Clavijo, Pablo , Coelho, Matthew , Ng, Kevin , Mugarza, Edurne , Moore, Chris , Rana, Sareena , Caswell, Deborah , Murillo, Miguel , Hancock, David , Argyris, Prokopios , Brown, William , Durfee, Cameron , Larson, Lindsay , Vogel, Rachel , Suarez-Bonnet, Alejandro Alejandro , Priestnall, Simon , East, Philip , Ross, Sarah , Kassiotis, George , Molina-Arcas, Miriam , Swanton, Charles , Harris, Reuben and Downward, Julian
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title
Language
English
Formats
Publication information
Publisher
Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Subjects
More information
Scope and Contents
Contents
Mutations in oncogenes such as KRAS and EGFR cause a high proportion of lung cancers. Drugs targeting these proteins cause tumour regression but ultimately fail to cure these cancers, leading to intense interest in how best to combine them with other treatments, such as immunotherapies. However, preclinical systems for studying the interaction of l...
Alternative Titles
Full title
An immunogenic model of KRAS-mutant lung cancer for study of targeted therapy and immunotherapy combinations
Authors, Artists and Contributors
Author / Creator
Sophie De Carne Trecesson
Law, Emily
Romero-Clavijo, Pablo
Coelho, Matthew
Ng, Kevin
Mugarza, Edurne
Moore, Chris
Rana, Sareena
Caswell, Deborah
Murillo, Miguel
Hancock, David
Argyris, Prokopios
Brown, William
Durfee, Cameron
Larson, Lindsay
Vogel, Rachel
Suarez-Bonnet, Alejandro Alejandro
Priestnall, Simon
East, Philip
Ross, Sarah
Kassiotis, George
Molina-Arcas, Miriam
Swanton, Charles
Harris, Reuben
Downward, Julian
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_proquest_journals_2506028203
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2506028203
Other Identifiers
E-ISSN
2692-8205
DOI
10.1101/2020.12.22.423126
How to access this item
https://www.proquest.com/docview/2506028203?pq-origsite=primo&accountid=13902
