TNF signalling fine-tunes Langerhans cell transcriptional programmes mediating adaptive immunity
TNF signalling fine-tunes Langerhans cell transcriptional programmes mediating adaptive immunity
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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English
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press
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ABSTRACT Langerhans cells (LCs) reside in the epidermis as a dense network of immune system sentinels, coordinating both immunogenic and tolerogenic immune responses. To determine molecular switches directing induction of LC immune activation, we performed mathematical modelling of gene regulatory networks identified by single cell RNA sequencing o...
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TNF signalling fine-tunes Langerhans cell transcriptional programmes mediating adaptive immunity
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TN_cdi_proquest_journals_2506312374
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2506312374
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E-ISSN
2692-8205
DOI
10.1101/2021.02.07.430111
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https://www.proquest.com/docview/2506312374?pq-origsite=primo&accountid=13902