Log in to save to my catalogue

TNF signalling fine-tunes Langerhans cell transcriptional programmes mediating adaptive immunity

TNF signalling fine-tunes Langerhans cell transcriptional programmes mediating adaptive immunity

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2506312374

TNF signalling fine-tunes Langerhans cell transcriptional programmes mediating adaptive immunity

About this item

Full title

TNF signalling fine-tunes Langerhans cell transcriptional programmes mediating adaptive immunity

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

Journal title

bioRxiv, 2021-02

Language

English

Formats

Publication information

Publisher

Cold Spring Harbor: Cold Spring Harbor Laboratory Press

More information

Scope and Contents

Contents

ABSTRACT Langerhans cells (LCs) reside in the epidermis as a dense network of immune system sentinels, coordinating both immunogenic and tolerogenic immune responses. To determine molecular switches directing induction of LC immune activation, we performed mathematical modelling of gene regulatory networks identified by single cell RNA sequencing o...

Alternative Titles

Full title

TNF signalling fine-tunes Langerhans cell transcriptional programmes mediating adaptive immunity

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_proquest_journals_2506312374

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_proquest_journals_2506312374

Other Identifiers

E-ISSN

2692-8205

DOI

10.1101/2021.02.07.430111